SITE PROFILE

Founded in 2005 by visionary Managing Director Dr. Johan Lombaard, Josha Research began as a dream and has grown into one of the world’s leading research
clinics. Located in the heart of Bloemfontein, the clinic operates from a beautifully restored historic building that has been carefully renovated and modernized—reflecting both its rich heritage and its commitment to cutting-edge medical research.

Josha Research is supported by a multidisciplinary team of experts, including medical doctors, registered nurses, pharmacists, laboratory technicians, data
capturers, and administrative staff. Together, they ensure the smooth execution of every study. The clinic specializes in Phase 1 to Phase 3 clinical trials and has
successfully conducted more than 120 clinical trials, building a strong track record of quality, reliability, and impact.

In 2009, Josha Research established a Community Advisory Board (CAB), bringing together people of diverse backgrounds and interests. The CAB meets monthly to
discuss issues of mutual importance and regularly organizes community outreach programs to educate local communities on the value and impact of clinical research. This ongoing dialogue strengthens trust and ensures that research remains both relevant and inclusive.

The clinic’s recruitment team plays a vital role in connecting with the community, reaching hundreds of potential participants each month for enrollment into clinical
trials. Their efforts help ensure timely recruitment, diverse representation, and strong community engagement.

The facility features a state-of-the-art laboratory equipped with centrifuges, incubators, and ultra-low cold storage units capable of maintaining temperatures
down to -80°C. Josha Research is also distinguished as the only facility in the Free State and Northern Cape with Bio Safety cabinets for PBMC (Peripheral Blood
Mononuclear Cell) processing, underscoring its dedication to excellence and innovation.

A fully equipped on-site pharmacy further enhances the clinic’s capabilities, managing both investigational products for research and prescribed medications for
participants. The pharmacy ensures safe storage, precise dispensing, and full compliance with regulatory standards.

Supporting these core functions are the Data, Administration, and Quality Assurance departments, which safeguard the accuracy, transparency, and integrity of all study information through diligent checks and strict adherence to protocols.

Finally, with 24-hour on-site security and a comprehensive CCTV system, Josha Research prioritizes the safety of participants, staff, and visitors, creating a secure
and trusted environment for world-class clinical research.

THE SITE CONSISTS OF THE FOLLOWING AMENITIES

  • All areas are access controlled and with air conditioning
  • Large basement parking garage across the street in the basement of the hotel
  • Reception area with a large waiting area
  • Large, well-planned clinic area with patient washrooms and five examination rooms
  • Well-equipped transit laboratory
  • PBMC laboratory
  • Access- and temperature-controlled pharmacy
  • Vaccine Pharmacy
  • Two kitchens
  • Large recruitment office with telephones for participant contact
  • Nine offices
  • Personnel washrooms
  • Access-controlled filing room
  • Two monitoring offices with internet access
  • Large boardroom with conference telephone
  • Three counseling rooms
  • Training area for up to 20 people, suitable for small conferences

AVAILABLE EQUIPMENT

All applicable equipment are calibrated annually according to international standards, with certificates immediately available on request

  • Emergency trolley complying with local MCC requirements
  • Electronic sphygmomanometer
  • Self-interpreting ECG machine
  • Electronic temperature-monitoring systems
  • Welch Allyn ENT sets in all examination rooms
  • Welch Allyn Spirometer
  • Electronic scales
  • Stadiometer
  • 2 – 8ºC Fridges
  • -20ºC Freezers
  • -80ºC Freezers
  • Centrifuges
  • Cold centrifuges
  • ADSL telephone lines
  • Internet access
  • Siemens Ultrasound for sonars and Doppler
  • Steam steriliser
  • Microscopes
  • Biosafety Cabinets

FIELDS OF RESEARCH INTEREST AND PREVIOUS TRIALS

  • Infectious Diseases – HIV, TB and Covid 19
  • Cardiovascular Diseases – Cholesterol, Cardiac Dysrhythmia    7 Cardiac Failure
  • Diabetes type 1 and 2
  • Endocrinological
  • Gastro-Intestinal Diseases
  • Respiratory Diseases Asthma – COPD, Influenza, and Pneumonia
  • Orthopedic Conditions – Osteoarthritis and Osteoporosis
  • Neurological Diseases
  • Nephrological Diseases
  • Dermatological Diseases
  • Haematological Diseases
  • Urological Diseases
  • Gynaecological Diseases